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Ribonuclease 1: A Key Player in RNA Degradation

The RNASE1 gene encodes a member of the ribonuclease A superfamily. The encoded protein is a monomeric ribonuclease with specificity for uridine residues at the 3′-side of the scission site. This enzyme cleaves RNA, initiating a degradation pathway that ultimately leads to the destruction of the RNA molecule. Ribonucleases play essential roles in various aspects…

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Microtubule-Associated Protein Tau: Structure, Function, and Role in Neurodegenerative Diseases

Microtubule-associated protein tau (MAPT) is a crucial protein in the human brain, playing a central role in the development and maintenance of neuronal microtubules. It is encoded by the MAPT gene and is primarily expressed in neurons. Tau protein’s main function is to stabilize and promote the assembly of microtubules, which are part of the…

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